Shengduo Liu

Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders

Ailian Wang, Chen Chen, Mei Chen et al. · Nature Cell Biology · 2024 · 65 citations

Innate Immune Sensing, Autoimmune Disease, Disease Mechanism +11

AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity

Qian Zhang, Shengduo Liu, Chen‐Song Zhang et al. · Molecular Cell · 2022 · 64 citations

Signal Transduction, Signaling Pathway, Cell Signaling +7

IRF3 activates RB to authorize cGAS-STING–induced senescence and mitigate liver fibrosis

Qirou Wu, Xiaohong Leng, Qian Zhang et al. · Science Advances · 2024 · 61 citations · Full text

Liver Fibrosis, Immunology, Interferon Genes +20

Microglial cGAS–STING signaling underlies glaucoma pathogenesis

Yutong Liu, Ailian Wang, Chen Chen et al. · Proceedings of the National Academy of Sciences · 2024 · 27 citations · Full text

Ocular Disease, Innate Immune System, Immunology +17

Targeting proteostasis of the HEV replicase to combat infection in preclinical models

Fei Zhang, Ling-Dong Xu, Qian Zhang et al. · Journal of Hepatology · 2022 · 18 citations

Viral Replication, Molecular Virology, Preclinical Models +8