Shingo Sugahara

PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

Dean Thumkeo, Siwakorn Punyawatthananukool, Somsak Prasongtanakij et al. · Cell Reports · 2022 · 108 citations · Full text

Role of JAK-STAT signaling in the pathogenic behavior of fibroblast-like synoviocytes in rheumatoid arthritis: Effect of the novel JAK inhibitor peficitinib

Takashi Emori, Michiko Kasahara, Shingo Sugahara et al. · European Journal of Pharmacology · 2020 · 46 citations · Full text

Immunology, Immune Regulation, Pathology +25

Constitutive Activation of Integrin α9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis

Takashi Emori, Jun Hirose, Kotoko Ise et al. · The Journal of Immunology · 2017 · 29 citations · Full text

The effects of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on T-cell-related cytokine production in vitro and in vivo

Satoshi Yamamoto, Shingo Sugahara, Ryo Naito et al. · European Journal of Pharmacology · 2006 · 25 citations

Inflammation, Cytokine, T-cell-related Cytokine Production +11

Amelioration of collagen-induced arthritis in mice by a novel phosphodiesterase 7 and 4 dual inhibitor, YM-393059

Satoshi Yamamoto, Shingo Sugahara, Ken‐ichi Ikeda et al. · European Journal of Pharmacology · 2006 · 21 citations

Inflammation, Rheumatology, Dual Inhibitor +15