Takamitsu Hattori

SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling

Carmine Fedele, Shuai Li, Kai Wen Teng et al. · The Journal of Experimental Medicine · 2020 · 256 citations · Full text

Medicine, Oncology, Pharmacology +17

Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling.

Nobuyoshi Arima, M Kamio, Kazunori Imada et al. · The Journal of Experimental Medicine · 1992 · 94 citations · Full text

Life Sciences, Cell Biology, Immunology +8

Selective and noncovalent targeting of RAS mutants for inhibition and degradation

Kai Wen Teng, Steven T. Tsai, Takamitsu Hattori et al. · Nature Communications · 2021 · 84 citations · Full text

Medicine, Molecular Biology, Oncology +16

Broad Ranges of Affinity and Specificity of Anti-Histone Antibodies Revealed by a Quantitative Peptide Immunoprecipitation Assay

Shingo Nishikori, Takamitsu Hattori, Stephen M. Fuchs et al. · Journal of Molecular Biology · 2012 · 80 citations

Life Sciences, Immunology, Molecular Biology +12

Creating MHC-Restricted Neoantigens with Covalent Inhibitors That Can Be Targeted by Immune Therapy

Takamitsu Hattori, Lorenzo Maso, Kiyomi Y. Araki et al. · Cancer Discovery · 2022 · 72 citations · Full text

Life Sciences, Immunology, Oncology +17