Timothy B. Chaston

Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.

Timothy B. Chaston, David B. Lovejoy, Ralph Watts et al. · PubMed · 2003 · 192 citations

Chemoprevention Strategy, Iron Metabolism, Pharmacotherapy +21

Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells

Timothy B. Chaston, Bomee Chung, M Mascarenhas et al. · Gut · 2007 · 142 citations

Potent Antitumor Activity of Novel Iron Chelators Derived from Di-2-Pyridylketone Isonicotinoyl Hydrazone Involves Fenton-Derived Free Radical Generation

Timothy B. Chaston, Ralph Watts, Jun Yuan et al. · Clinical Cancer Research · 2004 · 119 citations

Cytotoxic iron chelators: characterization of the structure, solution chemistry and redox activity of ligands and iron complexes of the di-2-pyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues

Paul V. Bernhardt, Lorraine M. Caldwell, Timothy B. Chaston et al. · JBIC Journal of Biological Inorganic Chemistry · 2003 · 84 citations

Biochemistry, Natural Sciences, Coordination Complex +8

Hepcidin Decreases Iron Transporter Expression in Vivo in Mouse Duodenum and Spleen and in Vitro in THP-1 Macrophages and Intestinal Caco-2 Cells

Bomee Chung, Timothy B. Chaston, Joanne Marks et al. · Journal of Nutrition · 2009 · 81 citations

Inflammation, Hepatology, Heme Homeostasis +14