Ralph Watts

Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.

Timothy B. Chaston, David B. Lovejoy, Ralph Watts et al. · PubMed · 2003 · 192 citations

Chemoprevention Strategy, Iron Metabolism, Pharmacotherapy +21

Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1

Ralph Watts, Clare L. Hawkins, Prem Ponka et al. · Proceedings of the National Academy of Sciences · 2006 · 127 citations · Full text

Iron Metabolism, Lipid Peroxidation, No-induced Glutathione Efflux +19

Soil organic matter–hydrogen peroxide dynamics in the treatment of contaminated soils and groundwater using catalyzed H2O2 propagations (modified Fenton's reagent)

L BISSEY, J. L. Smith, Ralph Watts · Water Research · 2006 · 127 citations

Chemical Engineering, Environmental Chemistry, Engineering +7

Potent Antitumor Activity of Novel Iron Chelators Derived from Di-2-Pyridylketone Isonicotinoyl Hydrazone Involves Fenton-Derived Free Radical Generation

Timothy B. Chaston, Ralph Watts, Jun Yuan et al. · Clinical Cancer Research · 2004 · 119 citations

Identification of the di‐pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti‐tumour agents

E. Becker, David B. Lovejoy, Judith M. Greer et al. · British Journal of Pharmacology · 2003 · 102 citations · Full text