Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer

Taekyoung Kwak, Fang Wang, Hui Deng, +19

Cell Reports

ImmunologyImmune RegulationPathologyImmunoeditingImmunologic Mechanism +23

Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis

Taekyoung Kwak, Katherine Drews‐Elger, Ayse Burcu Ergonul, +11

Oncogene

Breast OncologySignaling PathwayDrug TargetingMedicineBreast Cancer +6

O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic β cells

Eun-Sil Kang, Dohyun Han, Jungeun Park, +6

Experimental Cell Research

Akt1 Ser473Signal TransductionMolecular PhysiologyPancreatic CancerApoptosis +7

Blockade of four-transmembrane L6 family member 5 (TM4SF5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative #

Hyung Won Ryu, Youngmee Kim, Suyong Choi, +5

Hepatology

Cooperation between integrin α5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity

Suyong Choi, Sin-Ae Lee, Taekyoung Kwak, +5

Blood

Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells

Oisun Jung, Suyong Choi, Sunbok Jang, +16

Journal of Cell Science

Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial–mesenchymal transition

Minkyung Kang, Suyong Choi, Soo-Jin Jeong, +12

Biochemical Journal

TM4SF5 accelerates G1/S phase progression via cytosolic p27Kip1 expression and RhoA activity

Hyeonjung Kim, Minkyung Kang, Taekyoung Kwak, +3

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Signal TransductionSignaling PathwayG1/s Phase ProgressionMolecular PathwayNatural Sciences +9

Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function

Alexander E. Braley, Taekyoung Kwak, Joel Jules, +3

Journal of Biological Chemistry

The COOH-terminus of TM4SF5 in hepatoma cell lines regulates c-Src to form invasive protrusions via EGFR Tyr845 phosphorylation

Oisun Jung, Yoon-Ju Choi, Taekyoung Kwak, +4

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Signal TransductionHealth SciencesSignaling PathwayCell RegulationMedicine +10