Maria Faelth-Savitski

Catalytic in vivo protein knockdown by small-molecule PROTACs

Daniel P. Bondeson, Alina Mares, Ian E. Smith et al. · Nature Chemical Biology · 2015 · 1.3K citations · Full text

Biochemistry, Protein Assembly, Natural Sciences +2

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

Mikhail M. Savitski, Nico Zinn, Maria Faelth-Savitski et al. · Cell · 2018 · 222 citations · Full text

Identifying drug targets in tissues and whole blood with thermal-shift profiling

Jessica Perrin, Thilo Werner, Nils Kurzawa et al. · Nature Biotechnology · 2020 · 187 citations

Drug Target, Hit Identification, Medicine +12

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

Ujunwa Cynthia Okoye-Okafor, Boris Bartholdy, Jessy Cartier et al. · Nature Chemical Biology · 2015 · 174 citations · Full text

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +8

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo

Peng Wang, Gérard Joberty, Arjan Buist et al. · Acta Neuropathologica · 2017 · 114 citations · Full text

Tau Deubiquitination, Molecular Biology, Tau Interactome Mapping +17