Yoshiki Kusunoki

Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract

Risako Kon, Nobutomo Ikarashi, Chika Nagoya et al. · Journal of Ethnopharmacology · 2014 · 112 citations

Life Sciences, Immunology, Pharmacology +12

Morphine-Induced Constipation Develops With Increased Aquaporin-3 Expression in the Colon via Increased Serotonin Secretion

Risako Kon, Nobutomo Ikarashi, Akio Hayakawa et al. · Toxicological Sciences · 2015 · 96 citations

Medicine, Pharmacology, Pharmacotherapy +17

Xanthine oxidoreductase activity is correlated with insulin resistance and subclinical inflammation in young humans

Kahori Washio, Yoshiki Kusunoki, Takayo Murase et al. · Metabolism · 2017 · 75 citations

Medicine, Biochemistry, Endocrinology +16

Relationship between Aging-Related Skin Dryness and Aquaporins

Nobutomo Ikarashi, Risako Kon, Miho Kaneko et al. · International Journal of Molecular Sciences · 2017 · 66 citations · Full text

Medicine, Dermatology, Physiology +14

Hepatic early inflammation induces downregulation of hepatic cytochrome P450 expression and metabolic activity in the dextran sulfate sodium-induced murine colitis

Yoshiki Kusunoki, Nobutomo Ikarashi, Yoshitaka Hayakawa et al. · European Journal of Pharmaceutical Sciences · 2014 · 56 citations

Medicine, Biochemistry, Pharmacology +17