Svenja Mayer‐Wrangowski

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach

Julian Engel, André Richters, Matthäus Getlik et al. · Journal of Medicinal Chemistry · 2015 · 112 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Targeting the Hinge Glycine Flip and the Activation Loop: Novel Approach to Potent p38α Inhibitors

Kathrin E. Martz, Angelika Dorn, Benjamin Baur et al. · Journal of Medicinal Chemistry · 2012 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Dibenzosuberones as p38 Mitogen-Activated Protein Kinase Inhibitors with Low ATP Competitiveness and Outstanding Whole Blood Activity

Stefan Fischer, Heike K. Wentsch, Svenja Mayer‐Wrangowski et al. · Journal of Medicinal Chemistry · 2012 · 35 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Design, Synthesis, and Biological Evaluation of Novel Type I ¹ / ₂ p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine

Niklas M. Walter, Heike K. Wentsch, Mike Bührmann et al. · Journal of Medicinal Chemistry · 2017 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Optimized Target Residence Time: Type I Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R‐Spine

Heike K. Wentsch, Niklas M. Walter, Mike Bührmann et al. · Angewandte Chemie International Edition · 2017 · 26 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14