Concepedia

Mike Bührmann

MB

7

Publications

202

Citations

7

H-Index

2017

Active since

Affiliations

TU Dortmund University(Current)

University of Tübingen

Center for Translational Molecular Medicine

University of Cologne

Mike Bührmann is an author at TU Dortmund University specializing in chemical biology, computational biochemistry, and drug discovery.

Top concepts

Publications per year

2017–2022

7

Publications

7

Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors

Dennis Plenker, M Riedel, Johannes Brägelmann et al. · Science Translational Medicine · 2017 · 63 citations · Full text

Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK

Jakob Halekotte, Lydia Witt, Chiara Ianes et al. · Molecules · 2017 · 41 citations · Full text

Design, Synthesis, and Biological Evaluation of Novel Type I <sup>1</sup> / <sub>2</sub> p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine

Niklas M. Walter, Heike K. Wentsch, Mike Bührmann et al. · Journal of Medicinal Chemistry · 2017 · 30 citations · Full text

Optimized Target Residence Time: Type I Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R‐Spine

Heike K. Wentsch, Niklas M. Walter, Mike Bührmann et al. · Angewandte Chemie International Edition · 2017 · 25 citations

Covalent Lipid Pocket Ligands Targeting p38α MAPK Mutants

Mike Bührmann, Julia Hardick, Jörn Weisner et al. · Angewandte Chemie International Edition · 2017 · 18 citations

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