Concepedia

Author

Mike Bührmann

TU Dortmund University

Also Known As

Bührmann, Mike, M Buhrmann, Mike Bührmann

14

Publications

216

Citations

8

H-Index

14

Concepts

All Affiliations

TU Dortmund UniversityUniversity of TübingenCenter for Translational Molecular MedicineUniversity of Cologne
MB

About

Mike Bührmann is an author at TU Dortmund University specializing in chemical biology, computational biochemistry, and drug discovery.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

1

1

12

2

Natural Sciences

1

1

12

3

Biochemistry

1

1

12

4

Biomolecular Engineering

1

1

12

5

Chemical Biology

1

1

12

Mike Bührmann

×

7

Publications

202

Citations

7

H-Index

YearCitations

Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors

Dennis Plenker, M Riedel, Johannes Brägelmann,

Science Translational Medicine

2017

63

Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK

Jakob Halekotte, Lydia Witt, Chiara Ianes,

Molecules

2017

41

Design, Synthesis, and Biological Evaluation of Novel Type I <sup>1</sup> / <sub>2</sub> p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine

Niklas M. Walter, Heike K. Wentsch, Mike Bührmann,

Journal of Medicinal Chemistry

2017

30

Optimized Target Residence Time: Type I Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R‐Spine

Heike K. Wentsch, Niklas M. Walter, Mike Bührmann,

Angewandte Chemie International Edition

2017

25

Covalent Lipid Pocket Ligands Targeting p38α MAPK Mutants

Mike Bührmann, Julia Hardick, Jörn Weisner,

Angewandte Chemie International Edition

2017

18

Optimization of Covalent MKK7 Inhibitors <i>via</i> Crude Nanomole-Scale Libraries

Paul Gehrtz, Shir Marom, Mike Bührmann,

Journal of Medicinal Chemistry

2022

13

Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK

Mike Bührmann, Bianca Wiedemann, Matthias Müller,

PLoS ONE

2017

12

Page 1