Hijai R. Shin

AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

Hijai R. Shin, Hyun-Kyung Kim, Sungryong Oh et al. · Nature · 2016 · 435 citations · Full text

Cell Autophagy, Transcriptional Regulation, Signal Transduction +5

ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C

Chun-Yan Lim, Oliver B. Davis, Hijai R. Shin et al. · Nature Cell Biology · 2019 · 301 citations

Proteinlipid Interaction, Signal Transduction, Natural Sciences +8

NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

Oliver B. Davis, Hijai R. Shin, Chun-Yan Lim et al. · Developmental Cell · 2020 · 190 citations · Full text

Organelle Homeostasis, Signal Transduction, Oxysterol +10

Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition

Clive Yik‐Sham Chung, Hijai R. Shin, Charles A. Berdan et al. · Nature Chemical Biology · 2019 · 179 citations

Vacuolar H+-atpase Activates, Mitophagy, Cell Autophagy +13

Negative Regulation of Hypoxic Responses via Induced Reptin Methylation

Jason S. Lee, Yun-Ho Kim, Ik Soo Kim et al. · Molecular Cell · 2010 · 163 citations · Full text

Redox Regulator, Physiology, Hypoxia (Medicine) +7