Summer E. Young

Protease-Activated Receptor (PAR) 1 and PAR4 Differentially Regulate Factor V Expression from Human Platelets

Matthew T. Duvernay, Summer E. Young, David Gailani et al. · Molecular Pharmacology · 2013 · 73 citations · Full text

Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354

Wandong Wen, Summer E. Young, Matthew T. Duvernay et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 41 citations · Full text

Molecular Pharmacology, Substituted Indoles, Biochemistry +7

Synthesis of Indole Derived Protease-Activated Receptor 4 Antagonists and Characterization in Human Platelets

Summer E. Young, Matthew T. Duvernay, M. Schulte et al. · PLoS ONE · 2013 · 33 citations · Full text

Indole-based Par4 Antagonists, Pharmacotherapy, Molecular Pharmacology +17

Development of a Series of (1-Benzyl-3-(6-methoxypyrimidin-3-yl)-5-(trifluoromethoxy)-1<i>H</i>-indol-2-yl)methanols as Selective Protease Activated Receptor 4 (PAR4) Antagonists with in Vivo Utility and Activity Against γ-Thrombin

Kayla J. Temple, Matthew T. Duvernay, Summer E. Young et al. · Journal of Medicinal Chemistry · 2016 · 14 citations · Full text

Peptide Science, Pharmacotherapy, Par4 Ic50 +22