Mykhaylo V. Ruchko

Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells

Mykhaylo V. Ruchko, Olena M. Gorodnya, Susan P. LeDoux et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2004 · 97 citations

Life Sciences, Cell Biology, Molecular Biology +16

Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia/reperfusion

Xi‐Ming Yang, Lin Cui, James R. White et al. · Basic Research in Cardiology · 2015 · 67 citations · Full text

Life Sciences, Cardiology, Cell Biology +14

The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells

Mykhaylo V. Ruchko, Olena M. Gorodnya, Andres Zuleta et al. · Free Radical Biology and Medicine · 2010 · 59 citations

Life Sciences, Genetics, Molecular Biology +15

Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance

Larysa V. Yuzefovych, Viktor M. Pastukh, Mykhaylo V. Ruchko et al. · PLoS ONE · 2019 · 59 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences

Mark N. Gillespie, Victor Pastukh, Chang Zhang et al. · International Journal of COPD · 2011 · 58 citations · Full text

Life Sciences, Genetics, Molecular Biology +13