Olena M. Gorodnya

Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells

Mykhaylo V. Ruchko, Olena M. Gorodnya, Susan P. LeDoux et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2004 · 97 citations

Life Sciences, Cell Biology, Molecular Biology +16

Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteria-induced vascular injury in perfused rat lungs

Jamie L. Kuck, Boniface Obiako, Olena M. Gorodnya et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2015 · 77 citations · Full text

Life Sciences, Microbiology, Molecular Biology +14

The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells

Mykhaylo V. Ruchko, Olena M. Gorodnya, Andres Zuleta et al. · Free Radical Biology and Medicine · 2010 · 59 citations

Life Sciences, Genetics, Molecular Biology +15

Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences

Mark N. Gillespie, Victor Pastukh, Chang Zhang et al. · International Journal of COPD · 2011 · 58 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop region

Viktor M. Pastukh, Olena M. Gorodnya, Mark N. Gillespie et al. · Free Radical Biology and Medicine · 2016 · 56 citations · Full text

Life Sciences, Genetics, Molecular Biology +16