Jack P. Kennedy

Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility

N.R. Silvaggi, Grant E. Boldt, Mark S. Hixon et al. · Chemistry & Biology · 2007 · 128 citations

Microbial Toxin, Toxinology, Biochemistry +3

Identification of a Potent Botulinum Neurotoxin A Protease Inhibitor Using in Situ Lead Identification Chemistry

Grant E. Boldt, Jack P. Kennedy, Kim D. Janda · Organic Letters · 2006 · 113 citations · Full text

Toxinology, Lead Identification, Chemical Biology +16

Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding

Nicole Speed, Christine Saunders, Adeola R. Davis et al. · PLoS ONE · 2011 · 106 citations · Full text

Dysregulation of the Norepinephrine Transporter Sustains Cortical Hypodopaminergia and Schizophrenia-Like Behaviors in Neuronal Rictor Null Mice

Michael Siuta, Sabrina D. Robertson, Heidi Kocalis et al. · PLoS Biology · 2010 · 94 citations · Full text

Neuropsychology, Psychotropic Medication, Neurotransmitter +20

Synthesis, Characterization and Development of a High-Throughput Methodology for the Discovery of Botulinum Neurotoxin A Inhibitors

Grant E. Boldt, Jack P. Kennedy, Mark S. Hixon et al. · Journal of Combinatorial Chemistry · 2006 · 72 citations · Full text

Drug Target, High-throughput Methodology, Biochemistry +15