Grant E. Boldt

Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility

N.R. Silvaggi, Grant E. Boldt, Mark S. Hixon et al. · Chemistry & Biology · 2007 · 128 citations

Microbial Toxin, Toxinology, Biochemistry +3

Identification of a Potent Botulinum Neurotoxin A Protease Inhibitor Using in Situ Lead Identification Chemistry

Grant E. Boldt, Jack P. Kennedy, Kim D. Janda · Organic Letters · 2006 · 113 citations · Full text

Toxinology, Lead Identification, Chemical Biology +16

Synthesis, Characterization and Development of a High-Throughput Methodology for the Discovery of Botulinum Neurotoxin A Inhibitors

Grant E. Boldt, Jack P. Kennedy, Mark S. Hixon et al. · Journal of Combinatorial Chemistry · 2006 · 72 citations · Full text

Drug Target, High-throughput Methodology, Biochemistry +15

Light Chain of Botulinum Neurotoxin Serotype A:  Structural Resolution of a Catalytic Intermediate^,

Zhuji Fu, Sheng Chen, Michael R. Baldwin et al. · Biochemistry · 2006 · 61 citations

Identification of a botulinum neurotoxin A protease inhibitor displaying efficacy in a cellular model

Grant E. Boldt, Lisa M. Eubanks, Kim D. Janda · Chemical Communications · 2006 · 51 citations

Microbial Toxin, Toxinology, Biochemistry +14