Adenosine Monophosphate-Activated Protein Kinase Suppresses Vascular Smooth Muscle Cell Proliferation Through the Inhibition of Cell Cycle Progression

Motoyuki Igata, Hiroyuki Motoshima, Kaku Tsuruzoe, +11

Circulation Research

CRTC3 links catecholamine signalling to energy balance

Youngsup Song, Judith Y. Altarejos, Mark O. Goodarzi, +14

Nature

Energy HomeostasisMolecular PhysiologySignal TransductionNeurophysiologyEnergy Balance +4

Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway

Yoshiaki Hirashima, Kaku Tsuruzoe, Shintaro Kodama, +5

Journal of Endocrinology

Phosphatidylinositol 3-Kinase/akt PathwayInsulin SignalingReceptor Tyrosine KinaseProtein DegradationCell Signaling +14

Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice

Satoko Hanatani, Hiroyuki Motoshima, Yuki Takaki, +11

Journal of Clinical Biochemistry and Nutrition

Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice

Atsuyuki Tsutsumi, Hiroyuki Motoshima, Tatsuya Kondo, +12

Biochemical and Biophysical Research Communications

ObesityMetabolic SyndromeCaloric RestrictionEnergy HomeostasisLiver Physiology +10

Identification of microRNA that represses IRS-1 expression in liver

Kaoru Ono, Motoyuki Igata, Tatsuya Kondo, +10

PLoS ONE

PathologyIrs-1 ExpressionIrs-1 GeneInsulin SignalingObesity +21

Measurement of small fibre pain threshold values for the early detection of diabetic polyneuropathy

Daisuke Kukidome, Takeshi Nishikawa, Miki Sato, +7

Diabetic Medicine

AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells

Kazuhiko Nakamaru, Kazuya Matsumoto, Tetsuya Taguchi, +9

Biochemical and Biophysical Research Communications

Insulin SignalingSignal TransductionSignaling PathwayG Protein-coupled ReceptorAmp-activated Protein Kinase +8

Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes

Katsutoshi Miyagawa, Tatsuya Kondo, Rieko Goto, +9

Cardiovascular Diabetology

Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials

Tatsuya Kondo, Kaoru Ono, Sayaka Kitano, +10

EBioMedicine