Concepedia

Valérie Reader

VR

6

Publications

1.9K

Citations

6

H-Index

2001

Active since

Affiliations

CellCentric (United Kingdom)(Current)

Valérie Reader is an author at CellCentric (United Kingdom) specializing in drug discovery, natural sciences, and medicine.

ORCID

Top concepts

Publications per year

2001–2024

6

Publications

6

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

Marcus Bantscheff, Dirk Eberhard, Yann Abraham et al. · Nature Biotechnology · 2007 · 1K citations

, , +9

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Marcus Bantscheff, Carsten Hopf, Mikhail M. Savitski et al. · Nature Biotechnology · 2011 · 661 citations

, , +10

Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders

David Harrison, Andy Billinton, Mark G. Bock et al. · Journal of Medicinal Chemistry · 2023 · 53 citations · Full text

Reversal of High Fat Diet-Induced Obesity, Systemic Inflammation, and Astrogliosis by the NLRP3 Inflammasome Inhibitors NT-0249 and NT-0796

Peter Thornton, Valérie Reader, Zsofia Digby et al. · Journal of Pharmacology and Experimental Therapeutics · 2024 · 46 citations · Full text

Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics

Gérard Joberty, Markus Böesche, Jack A. Brown et al. · ACS Chemical Biology · 2016 · 42 citations

, , +17

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