Concepedia

Author

Gaku Oshikawa

Tokyo Medical and Dental University

Also Known As

G Oshikawa, G. Oshikawa, GAKU OSHIKAWA, Gaku Oshikawa

49

Publications

512

Citations

14

H-Index

31

Concepts

All Affiliations

Tokyo Medical and Dental University
GO

About

Gaku Oshikawa is an author at Tokyo Medical and Dental University specializing in medicine, cell biology, and immunology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

6

6

150

2

Cell Biology

5

5

135

3

Immunology

4

4

122

4

Health Sciences

1

1

15

5

Gastroenterology

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1

15

Gaku Oshikawa

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12

Publications

331

Citations

12

H-Index

YearCitations

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia

Ayako Nogami, Gaku Oshikawa, Keigo Okada,

Oncotarget

2015

63

c-Cbl and Cbl-b Ligases Mediate 17-Allylaminodemethoxygeldanamycin-induced Degradation of Autophosphorylated Flt3 Kinase with Internal Tandem Duplication through the Ubiquitin Proteasome Pathway

Gaku Oshikawa, Toshikage Nagao, Nan Wu,

Journal of Biological Chemistry

2011

45

Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway

Tetsuya Kurosu, Nan Wu, Gaku Oshikawa,

APOPTOSIS

2010

42

Inhibition of the PI3K/Akt/GSK3 Pathway Downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD Downregulates DNA Damage-Induced Chk1 Activation as Well as G2/M Arrest and Prominently Enhances Induction of Apoptosis

Tetsuya Kurosu, Toshikage Nagao, Nan Wu,

PLoS ONE

2013

40

Proliferation and Survival Signaling from Both Jak2-V617F and Lyn Involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 Cell Line Newly Established from Acute Myeloid Leukemia Transformed from Polycythemia Vera

Toshikage Nagao, Tetsuya Kurosu, Yoshihiro Umezawa,

PLoS ONE

2014

25

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2

Shinya Ishida, Hiroki Akiyama, Yoshihiro Umezawa,

Oncotarget

2018

25

Clinical features and risk factors for developing varicella zoster virus dissemination following hematopoietic stem cell transplantation

Yoshihiro Umezawa, Kazuhiko Kakihana, Gaku Oshikawa,

Transplant Infectious Disease

2014

19

Extranodal NK/T cell lymphoma, nasal type, of the small intestine diagnosed by double-balloon endoscopy

Shihoko Wakabayashi, Ayako Arai, Gaku Oshikawa,

International Journal of Hematology

2009

15

DNA Damage Stress and Inhibition of Jak2-V617F Cause Its Degradation and Synergistically Induce Apoptosis through Activation of GSK3β

Toshikage Nagao, Gaku Oshikawa, Nan Wu,

PLoS ONE

2011

15

Acute promyelocytic leukemia presenting as recurrent spinal myeloid sarcomas 3 years before developing leukemia: A case report with review of literature

Tomoko Yamashita, Akihiko Nishijima, Yuma Noguchi,

Clinical Case Reports

2019

15

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