Asaad Nematalla

Discovery of 5-[5-Fluoro-2-oxo-1,2- dihydroindol-(3<i>Z</i>)-ylidenemethyl]-2,4- dimethyl-1<i>H</i>-pyrrole-3-carboxylic Acid (2-Diethylaminoethyl)amide, a Novel Tyrosine Kinase Inhibitor Targeting Vascular Endothelial and Platelet-Derived Growth Factor Receptor Tyrosine Kinase

Li Sun, Chris Liang, Sheri Shirazian et al. · Journal of Medicinal Chemistry · 2003 · 520 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185erbB) tyrosine kinases

Li Sun, Jean Cui, Congxin Liang et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

A Novel Sialidase Capable of Cleaving 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid (KDN)

Y.T. Li, Jeffrey A. Yuziuk, S.C. Li et al. · Archives of Biochemistry and Biophysics · 1994 · 28 citations

Life Sciences, Biochemistry, Biotechnology +12

An improved synthesis of 4-azido-4-deoxy- and 4-amino-4-deoxy-α,α-trehalose and their epimers

Rafik W. Bassily, Ramadan I. El-Sokkary, Basim Azmy Silwanis et al. · Carbohydrate Research · 1993 · 28 citations

Pharmacy, Biochemistry, Chemistry +8

Exploratory Process Development of Lorlatinib

Bryan Li, Richard W. Barnhart, Jacqui Hoffman et al. · Organic Process Research & Development · 2018 · 26 citations

Pharmacy, Chemistry, Medicinal Chemistry +16