John J. Graziotto

Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease

Oliver Cooper, Hyemyung Seo, Shaida A. Andrabi et al. · Science Translational Medicine · 2012 · 506 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells

Philip Seibler, John J. Graziotto, Hyun‐Ghang Jeong et al. · Journal of Neuroscience · 2011 · 384 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells

Kan Cao, John J. Graziotto, Cecilia D. Blair et al. · Science Translational Medicine · 2011 · 346 citations

Education, Cell Biology, Molecular Biology +15

Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation

Sun Young Chung, Sarah Kishinevsky, Joseph R. Mazzulli et al. · Stem Cell Reports · 2016 · 208 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Three Gene-Targeted Mouse Models of RNA Splicing Factor RP Show Late-Onset RPE and Retinal Degeneration

John J. Graziotto, Michael H. Farkas, Kinga M. Bujakowska et al. · Investigative Ophthalmology & Visual Science · 2010 · 87 citations · Full text

Medicine, Genetics, Ophthalmology +14