Claudia Fuchs

Mapping Pathological Phenotypes in a Mouse Model of CDKL5 Disorder

Elena Amendola, Yang Zhan, Camilla Mattucci et al. · PLoS ONE · 2014 · 208 citations · Full text

Cyclin-dependent Kinase-like 5, Cdkl5 Disorder, Neurotransmission +24

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

Claudia Fuchs, Stefania Trazzi, Roberta Torricella et al. · Neurobiology of Disease · 2014 · 143 citations · Full text

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

Stefania Trazzi, Valentina Maria Mitrugno, Emanuele Valli et al. · Human Molecular Genetics · 2011 · 113 citations · Full text

Brain Development, Sonic Hedgehog, Social Sciences +22

HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder

Stefania Trazzi, Claudia Fuchs, Rocchina Viggiano et al. · Human Molecular Genetics · 2016 · 111 citations · Full text

Brain Development, Genetics, Hdac4 Activity +19

CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder

Stefania Trazzi, Marianna De Franceschi, Claudia Fuchs et al. · Human Molecular Genetics · 2018 · 70 citations · Full text