Joan D. Ellis

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Daria J. Hazuda, Neville J. Anthony, Robert Gomez et al. · Proceedings of the National Academy of Sciences · 2004 · 332 citations · Full text

Hiv-1 Integrase, Immunology, Cell Culture +17

In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α_1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia

James C. Barrow, Philippe G. Nantermet, Harold G. Selnick et al. · Journal of Medicinal Chemistry · 2000 · 220 citations · Full text

Molecular Pharmacology, Urology, Pharmacological Study +12

First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates

Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 105 citations

In Vivo β-Secretase 1 Inhibition Leads to Brain Aβ Lowering and Increased α-Secretase Processing of Amyloid Precursor Protein without Effect on Neuregulin-1

Sethu Sankaranarayanan, Eric A. Price, Guoxin Wu et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 100 citations

Disposition and Pharmacokinetics of the Antimigraine Drug, Rizatriptan, in Humans

Kamlesh P. Vyas, Rita A. Halpin, Leslie A. Geer et al. · Drug Metabolism and Disposition · 2000 · 62 citations