Antibody targeting of E3 ubiquitin ligases for receptor degradation

Hadir Marei, Wen‐Ting K. Tsai, Yee-Seir Kee, +35

Nature

Interplay between RORγt, Egr3, and E Proteins Controls Proliferation in Response to Pre-TCR Signals

Hongkang Xi, Ruth Schwartz, Isaac Engel, +2

Immunity

Transcriptional RegulationPre-tcr SignalsSignal TransductionSignaling PathwayCell Regulation +7

Thymocyte Development in Early Growth Response Gene 1-Deficient Mice

Matthew L. Bettini, Hongkang Xi, Jeffrey Milbrandt, +1

The Journal of Immunology

IL-33 amplifies an innate immune response in the degenerating retina

Hongkang Xi, Kenneth J. Katschke, Yun Li, +13

The Journal of Experimental Medicine

Ocular DiseaseImmunologyImmune RegulationCell DeathImmunologic Mechanism +23

A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis

Kenneth J. Katschke, Karim Y. Helmy, Micah Steffek, +12

The Journal of Experimental Medicine

Crystal StructureComplement Reverses InflammationComplement PathwaysImmunologyImmunologic Mechanism +22

Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy

Kenneth J. Katschke, Hongkang Xi, Christian L. Cox, +12

Scientific Reports

Complement Receptor of the Ig Superfamily Enhances Complement-Mediated Phagocytosis in a Subpopulation of Tissue Resident Macrophages

Nick N. Gorgani, Jeannie Q. He, Kenneth J. Katschke, +5

The Journal of Immunology

ImmunologyImmunologic MechanismComplement ReceptorImmunotherapyInflammation +15

Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement

Kenneth J. Katschke, Scott Stawicki, Jianping Yin, +9

Journal of Biological Chemistry

Crystal StructureImmunologyImmunologic MechanismAntigen ProcessingFunctional Analysis +17

Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1

Hongkang Xi, Kenneth J. Katschke, Karim Y. Helmy, +7

The Journal of Experimental Medicine

Inhibitory Receptor Clm-1Immune RegulationImmunologyImmune SystemImmunotherapy +17

Early Growth Response Gene 3 Regulates Thymocyte Proliferation during the Transition from CD4−CD8− to CD4+CD8+1

Hongkang Xi, Gilbert J. Kersh

The Journal of Immunology

Calpha ExpressionTranscriptional RegulationDevelopmental BiologyAlphabeta LineageCell Division +12