Monica Abdelmalak - Concepedia

Author

Monica Abdelmalak

Center for Cancer Research

Also Known As

Monica Abdelmalak

Publications

432

Citations

H-Index

Concepts

All Affiliations

Center for Cancer Research National Cancer Institute National Institutes of Health Purdue University West Lafayette University of Minnesota

About

Monica Abdelmalak is an author at Center for Cancer Research specializing in biochemistry, natural sciences, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	5	5	146
2	Biochemistry	5	5	146
3	Medicine	4	4	130
4	Chemical Biology	2	2	54
5	Molecular Biology	2	2	50

Monica Abdelmalak

Publications

432

Citations

H-Index

Page 1

	Year	Citations
Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2) Rui Gao, Matthew J. Schellenberg, Shar-yin N. Huang, Journal of Biological Chemistry	2014	117
Isoquinoline-1,3-diones as Selective Inhibitors of Tyrosyl DNA Phosphodiesterase II (TDP2) Jayakanth Kankanala, Christophe Marchand, Monica Abdelmalak, Journal of Medicinal Chemistry	2016	65
Synthesis and Biological Evaluation of Nitrated 7-, 8-, 9-, and 10-Hydroxyindenoisoquinolines as Potential Dual Topoisomerase I (Top1)–Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors Trung Xuan Nguyen, Monica Abdelmalak, Christophe Marchand, Journal of Medicinal Chemistry	2015	58
Discovery of Potent Indenoisoquinoline Topoisomerase I Poisons Lacking the 3-Nitro Toxicophore Daniel E. Beck, Monica Abdelmalak, Wei Lv, Journal of Medicinal Chemistry Medicinal ChemistryBiochemistryMedicineNatural SciencesToxicology	2015	48
Investigation of the Structure–Activity Relationships of Aza-A-Ring Indenoisoquinoline Topoisomerase I Poisons Daniel E. Beck, P. Venkat Reddy, Wei Lv, Journal of Medicinal Chemistry	2016	46
Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2 Christophe Marchand, Monica Abdelmalak, Jayakanth Kankanala, ACS Chemical Biology Drug TargetTdp2 EnzymesMolecular BiologyChemical BiologyHuman Enzyme	2016	34
Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons Daniel E. Beck, Wei Lv, Monica Abdelmalak, Bioorganic & Medicinal Chemistry Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicine	2016	28
Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2) Lemao Yu, Zhu Hu, Yu Chen, European Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryBiochemistryNatural SciencesMedicine	2018	20
Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft Bradley R. Kossmann, Monica Abdelmalak, Sophia Lopez, Bioorganic & Medicinal Chemistry Letters Enzyme Dna-binding CleftBiochemistryNatural SciencesOligonucleotideMolecular Biology	2016	16

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