Concepedia

Monica Abdelmalak

MA

9

Publications

432

Citations

9

H-Index

2014

Active since

Affiliations

Center for Cancer Research(Current)

National Cancer Institute

National Institutes of Health

Purdue University West Lafayette

University of Minnesota

Monica Abdelmalak is an author at Center for Cancer Research specializing in biochemistry, natural sciences, and drug discovery.

Top concepts

Publications per year

2014–2018

9

Publications

9

Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)

Rui Gao, Matthew J. Schellenberg, Shar-yin N. Huang et al. · Journal of Biological Chemistry · 2014 · 117 citations · Full text

Isoquinoline-1,3-diones as Selective Inhibitors of Tyrosyl DNA Phosphodiesterase II (TDP2)

Jayakanth Kankanala, Christophe Marchand, Monica Abdelmalak et al. · Journal of Medicinal Chemistry · 2016 · 65 citations · Full text

Synthesis and Biological Evaluation of Nitrated 7-, 8-, 9-, and 10-Hydroxyindenoisoquinolines as Potential Dual Topoisomerase I (Top1)–Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors

Trung Xuan Nguyen, Monica Abdelmalak, Christophe Marchand et al. · Journal of Medicinal Chemistry · 2015 · 58 citations · Full text

Discovery of Potent Indenoisoquinoline Topoisomerase I Poisons Lacking the 3-Nitro Toxicophore

Daniel E. Beck, Monica Abdelmalak, Wei Lv et al. · Journal of Medicinal Chemistry · 2015 · 48 citations · Full text

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Investigation of the Structure–Activity Relationships of Aza-A-Ring Indenoisoquinoline Topoisomerase I Poisons

Daniel E. Beck, P. Venkat Reddy, Wei Lv et al. · Journal of Medicinal Chemistry · 2016 · 46 citations · Full text

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