Jayakanth Kankanala

Design, Synthesis, Biochemical, and Antiviral Evaluations of C6 Benzyl and C6 Biarylmethyl Substituted 2-Hydroxylisoquinoline-1,3-diones: Dual Inhibition against HIV Reverse Transcriptase-Associated RNase H and Polymerase with Antiviral Activities

Sanjeev Kumar V. Vernekar, Zheng Liu, Éva Nagy et al. · Journal of Medicinal Chemistry · 2014 · 132 citations · Full text

Bioorganic Chemistry, Ribonuclease H, C6 Biarylmethyl +19

5′-Silylated 3′-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus

Sanjeev Kumar V. Vernekar, Li Qiu, Jing Zhang et al. · Journal of Medicinal Chemistry · 2015 · 85 citations · Full text

Isoquinoline-1,3-diones as Selective Inhibitors of Tyrosyl DNA Phosphodiesterase II (TDP2)

Jayakanth Kankanala, Christophe Marchand, Monica Abdelmalak et al. · Journal of Medicinal Chemistry · 2016 · 65 citations · Full text

Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus p7 as a Viable Class of Antivirals Targeting Virion Release

Toshana L. Foster, Gary S. Thompson, Arnout P. Kalverda et al. · Hepatology · 2013 · 62 citations · Full text

Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H

Jayakanth Kankanala, Karen A. Kirby, Feng Liu et al. · Journal of Medicinal Chemistry · 2016 · 61 citations · Full text

Ribonuclease H, Molecular Biology, Antiviral Drug +18