Nuclear localization and signalling activity of phosphoinositidase Cβ in Swiss 3T3 cells

Alberto M. Martelli, Raymond Gilmour, Valeria Bertagnolo, +3

Nature

Signal TransductionSignaling PathwayMolecular RegulationNatural SciencesMolecular Biology +9

A Role for Nuclear Phospholipase Cβ1 in Cell Cycle Control

Irene Faenza, Alessandro Matteucci, Lucia Manzoli, +7

Journal of Biological Chemistry

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

Alberto M. Martelli, Pier Luigi Tazzari, Giovanna Tabellini, +6

Leukemia

Hematological MalignancyAll-trans-retinoic AcidMedicineMalignant Blood DisorderPharmacology +9

Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS

Matilde Y. Follo, Carlo Finelli, Sara Mongiorgi, +10

Proceedings of the National Academy of Sciences

Hematological MalignancyMixed-phenotype Acute LeukemiaAcute Myeloid LeukemiaMds PatientsPharmacology +11

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-κB activation and cFLIPL up-regulation

Roberta Bortul, Pier Luigi Tazzari, Alessandra Cappellini, +6

Leukemia

Signal TransductionSignaling PathwayCell RegulationMedicineApoptosis +10

Essential role for nuclear phospholipase C beta1 in insulin-like growth factor I-induced mitogenesis.

Lucia Manzoli, Billi Am, Silvia Rubbini, +5

PubMed

Nuclear SignalingNuclear Plc SignalingCellular PhysiologyInsulin SignalingSignaling Pathway +16

Phosphoinositide signaling in nuclei of Friend cells: phospholipase C beta down-regulation is related to cell differentiation.

Alberto M. Martelli, Anna Maria Billi, R. S. Gilmour, +4

PubMed

Developmental BiologySignal TransductionSignaling PathwayReceptor Tyrosine KinaseImmunology +12

Mineral-Doped Poly(L-lactide) Acid Scaffolds Enriched with Exosomes Improve Osteogenic Commitment of Human Adipose-Derived Mesenchymal Stem Cells

Maria Giovanna Gandolfi, Chiara Gardin, Fausto Zamparini, +9

Nanomaterials

Nuclear but not cytoplasmic phospholipase C beta 1 inhibits differentiation of erythroleukemia cells.

Alessandro Matteucci, Irene Faenza, R. S. Gilmour, +6

PubMed

ApoptosisImmunologyCell CycleCellular PhysiologyCell Regulation +18

PLA-Based Mineral-Doped Scaffolds Seeded with Human Periapical Cyst-Derived MSCs: A Promising Tool for Regenerative Healing in Dentistry

Marco Tatullo, Gianrico Spagnuolo, Bruna Codispoti, +11

Materials

Tissue EngineeringEngineeringBiomaterials DesignBone RepairBiofabrication +18