Comprehensive Analysis of Hypermutation in Human Cancer

Brittany Campbell, Nicholas Light, David Fabrizio, +59

Cell

Somatic VariantCancer GenomicsComprehensive AnalysisMedicineCell Biology +3

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

Anirban Das, Sumedha Sudhaman, Daniel A. Morgenstern, +80

Nature Medicine

DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells

Jiil Chung, Yosef E. Maruvka, Sumedha Sudhaman, +52

Cancer Discovery

Cardiac troponin I mutations in Australian families with hypertrophic cardiomyopathy: clinical, genetic and functional consequences

Alessandra Doolan, Molly Tebo, Jodie Ingles, +7

Journal of Molecular and Cellular Cardiology

CardiomyopathyCardiovascular DiseaseMedicineGeneticsGenetic Epidemiology +8

Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study

Ayse B. Ercan, Melyssa Aronson, Nicholas R. Fernandez, +125

The Lancet Oncology

Family MedicineBiological LandscapeGenetic DisorderClinical GeneticsMedicine +3

Assessment of quality of life, information, and supportive care needs in patients with muscle and non-muscle invasive bladder cancer across the illness trajectory

Jiil Chung, Girish S. Kulkarni, Robin Morash, +5

Supportive Care in Cancer

Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti–PD-1 Monotherapy: A Report from the International RRD Consortium

Anirban Das, Nicholas R. Fernandez, Adrian Levine, +60

Cancer Discovery

Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset

Jiil Chung, Logine Negm, Vanessa Bianchi, +44

Journal of Clinical Oncology

Modifiable lifestyle behaviours impact the health‐related quality of life of bladder cancer survivors

Jiil Chung, Girish S. Kulkarni, Rodney H. Breau, +6

British Journal of Urology

Upfront Adjuvant Immunotherapy of Replication Repair–Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach

Trisha Larkin, Anirban Das, Vanessa Bianchi, +10

JCO Precision Oncology

Neuro-oncologyCancer ImmunosurveillanceOncologyGliomaUpfront Adjuvant Immunotherapy +8