Sumedha Sudhaman

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

Anirban Das, Sumedha Sudhaman, Daniel A. Morgenstern et al. · Nature Medicine · 2022 · 144 citations · Full text

Life Sciences, Immunology, Oncology +10

DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells

Jiil Chung, Yosef E. Maruvka, Sumedha Sudhaman et al. · Cancer Discovery · 2020 · 86 citations · Full text

Life Sciences, Genetics, Oncology +17

Evidence of mutations in <i>RIC3</i> acetylcholine receptor chaperone as a novel cause of autosomal-dominant Parkinson's disease with non-motor phenotypes

Sumedha Sudhaman, Uday B. Muthane, Madhuri Behari et al. · Journal of Medical Genetics · 2016 · 46 citations

Life Sciences, Genetics, Neurology +17

Discovery of a frameshift mutation in podocalyxin-like (PODXL) gene, coding for a neural adhesion molecule, as causal for autosomal-recessive juvenile Parkinsonism

Sumedha Sudhaman, Kameshwar Prasad, Madhuri Behari et al. · Journal of Medical Genetics · 2016 · 43 citations · Full text

Life Sciences, Genetics, Neurology +17

Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition

Brittany Campbell, Melissa A. Galati, Simone C. Stone et al. · Cancer Discovery · 2021 · 39 citations · Full text

Medicine, Genetics, Oncology +17