James Sipthorp - Concepedia

Author

James Sipthorp

The Francis Crick Institute ORCID

Also Known As

James Sipthorp, Sipthorp, J, Sipthorp, James

Publications

378

Citations

H-Index

Concepts

All Affiliations

The Francis Crick Institute Centre for Human Genetics Alzheimer’s Research UK University College London University of Oxford

About

James Sipthorp is an author at The Francis Crick Institute specializing in medicine, structural biology, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	42
2	Natural Sciences	1	1	23
3	Biochemistry	1	1	23
4	Biomedical Engineering	1	1	23
5	Biomolecular Engineering	1	1	23

James Sipthorp

Publications

202

Citations

H-Index

Page 1

	Year	Citations
A palmitoyl transferase chemical–genetic system to map ZDHHC-specific S-acylation Cory A. Ocasio, Marc P. Baggelaar, James Sipthorp, Nature Biotechnology	2024	37
Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen Benjamin N. Atkinson, David Steadman, Yuguang Zhao, MedChemComm	2019	27
A New Methodology for Incorporating Chiral Linkers into Stapled Peptides Juan Carlos Serrano, James Sipthorp, Wenshu Xu, ChemBioChem Peptide EngineeringMolecular BiologyBiomedical EngineeringChemical BiologyP53-derived Stapled Peptide	2017	23
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors Benjamin N. Atkinson, David Steadman, William Mahy, Bioorganic & Medicinal Chemistry Letters	2019	20
A Novel Methodology for the Incorporation of Chiral Linkers in Stapled Peptides J.R. Pedraza Serrano, James Sipthorp, Wenshu Xu Apollo (University of Cambridge)	2017	19
5-Phenyl-1,3,4-oxadiazol-2(3<i>H</i>)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit William Mahy, Nicky J. Willis, Yuguang Zhao, Journal of Medicinal Chemistry	2020	19
Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis Goran Tomić, Clare Sheridan, Alice Y. Refermat, Cell Reports Tumor BiologyPancreatic CancerDepleted Natural KillerMedicinePrimary Pdac Growth	2024	19
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit Nicky J. Willis, William Mahy, James Sipthorp, Journal of Medicinal Chemistry	2022	16
CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells Sougata Roy, James Sipthorp, Bidesh Mahata, iScience	2021	12
Visualization of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe James Sipthorp, Honorine Lebraud, Rebecca Gilley, Bioconjugate Chemistry	2017	10

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