A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

Nicole Almanzar, Jane Antony, Ankit S. Baghel, +131

Nature

Cell LineageDevelopmental BiologySingle-cell Transcriptomic AtlasSingle Cell SequencingMedicine +6

Ageing hallmarks exhibit organ-specific temporal signatures

Nicholas Schaum, Benoit Lehallier, Oliver Hãhn, +158

Nature

Signal TransductionAgingDevelopmental BiologyLongevityCellular Senescence +5

Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation

Jean Hausser, Afzal P Syed, Biter Bilen, +1

Genome Research

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Róbert Pálovics, Andreas Keller, Nicholas Schaum, +138

Nature

PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif

Christiane Rammelt, Biter Bilen, Mihaela Zavolan, +1

RNA

EngineeringNoncanonical PolyNatural SciencesRna SubstratesRecombinant Papd5 +8

Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function

Antoine de Morrée, Julian D.D. Klein, Qiang Gan, +7

Science

Genome-Wide Transcriptional Reorganization Associated with Senescence-to-Immortality Switch during Human Hepatocellular Carcinogenesis

Ayça Arslan-Ergül, Sevgi Baǧışlar, Özlen Konu, +15

PLoS ONE

Transcriptional RegulationSystems BiologyHcc TumorsMedicineLiver Physiology +11

Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets

Jia Zhao, Gefei Wang, Jingsi Ming, +162

Nature Computational Science

Artificial IntelligenceEngineeringMachine LearningDeep LearningData Science +8

Argonaute CLIP – A method to identify in vivo targets of miRNAs

Łukasz Jaśkiewicz, Biter Bilen, Jean Hausser, +1

Methods

Functional GenomicsEngineeringA MethodMedicineRna Biology +9

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome

Shixuan Liu, Camille Ezran, Michael F. Z. Wang, +159

Nature Communications