James H. Soper

A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease

Marc Brehme, Cindy Voisine, Thomas Rolland et al. · Cell Reports · 2014 · 590 citations · Full text

α-Synuclein–induced Aggregation of Cytoplasmic Vesicles in<i>Saccharomyces cerevisiae</i>

James H. Soper, Subhojit Roy, Anna Stieber et al. · Molecular Biology of the Cell · 2008 · 154 citations · Full text

Neurodegenerative Diseases, α-Synuclein–induced Aggregation, Lb-like Fibrils +15

 -Syn Suppression Reverses Synaptic and Memory Defects in a Mouse Model of Dementia with Lewy Bodies

Youngshin Lim, Victoria Kehm, E. B. Lee et al. · Journal of Neuroscience · 2011 · 116 citations · Full text

Neuropsychology, Brain Function, Synaptic Transmission +23

Aggregation of α-Synuclein in S. cerevisiae is Associated with Defects in Endosomal Trafficking and Phospholipid Biosynthesis

James H. Soper, Victoria Kehm, Christopher G. Burd et al. · Journal of Molecular Neuroscience · 2010 · 70 citations · Full text

Phospholipid Biosynthesis, Medicine, Natural Sciences +11

Cyclopentane-1,3-dione: A Novel Isostere for the Carboxylic Acid Functional Group. Application to the Design of Potent Thromboxane (A2) Receptor Antagonists

Carlo Ballatore, James H. Soper, Francesco Piscitelli et al. · Journal of Medicinal Chemistry · 2011 · 42 citations · Full text

Combinatorial Chemistry, Receptor Antagonists, Receptor Antagonist +18