Juan Pablo Maianti

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

Luke W. Koblan, Jordan L. Doman, Christopher Wilson et al. · Nature Biotechnology · 2018 · 943 citations · Full text

Bioinformatics, Systems Biology, Molecular Biological Method +13

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

Juan Pablo Maianti, Amanda McFedries, Zachariah H. Foda et al. · Nature · 2014 · 249 citations · Full text

Multiple Hormones, Biochemistry, Medicine +9

Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules

Dmitry L. Usanov, Alix I Chan, Juan Pablo Maianti et al. · Nature Chemistry · 2018 · 189 citations · Full text

Dna Nanotechnology, Biochemistry, Natural Sciences +10

Synthesis and Comparative Antibacterial Activity of Verdamicin C2 and C2a. A New Oxidation of Primary Allylic Azides in Dihydro[2<i>H</i>]pyrans

Stephen Hanessian, Janek Szychowski, Juan Pablo Maianti · Organic Letters · 2008 · 55 citations

Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme

Juan Pablo Maianti, G.A. Tan, Amedeo Vetere et al. · Nature Chemical Biology · 2019 · 51 citations

Insulin-degrading Enzyme, Insulin Signaling, Drug Discovery +1