Alix I Chan

Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules

Dmitry L. Usanov, Alix I Chan, Juan Pablo Maianti et al. · Nature Chemistry · 2018 · 189 citations · Full text

Dna Nanotechnology, Biochemistry, Natural Sciences +10

One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1

Thibault J. Harmand, Djenet Bousbaine, Alix I Chan et al. · Bioconjugate Chemistry · 2018 · 99 citations

Orthogonal Specificity, Engineering, Molecular Biology +23

Discovery of a Covalent Kinase Inhibitor from a DNA-Encoded Small-Molecule Library × Protein Library Selection

Alix I Chan, Lynn M. McGregor, Tara Jain et al. · Journal of the American Chemical Society · 2017 · 90 citations · Full text

Molecular Biology, Chemical Biology, Nucleic Acid Biomarkers +21

Discovery and molecular basis of subtype-selective cyclophilin inhibitors

Alexander A. Peterson, Aziz M. Rangwala, Manish Thakur et al. · Nature Chemical Biology · 2022 · 30 citations · Full text

Multimodal small-molecule screening for human prion protein binders

Andrew G. Reidenbach, Michael F. Mesleh, Dominick Casalena et al. · Journal of Biological Chemistry · 2020 · 27 citations · Full text