Nobuyuki Matsuhashi

Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial

Takuma Higurashi, Kunihiro Hosono, Hirokazu Takahashi et al. · The Lancet Oncology · 2016 · 335 citations

Post-polypectomy Patients, Surgical Oncology, Diabetes Management +10

Endogenous PPARγ mediates anti-inflammatory activity in murine ischemia-reperfusion injury

Atsushi Nakajima, Koichiro Wada, Hiroshi Miki et al. · Gastroenterology · 2001 · 215 citations · Full text

Inflammation, Medicine, Immunology +7

Increased Susceptibility of  Thymocytes to Apoptosis in Mice Lacking AIM, a Novel Murine Macrophage-derived Soluble Factor Belonging to the Scavenger Receptor Cysteine-rich Domain Superfamily

Toru Miyazaki, Yumiko Hirokami, Nobuyuki Matsuhashi et al. · The Journal of Experimental Medicine · 1999 · 206 citations · Full text

Cysteine-rich Domain, Apoptosis, Immune Regulation +18

Peroxisome proliferator-activated receptor γ ligands suppress colon carcinogenesis induced by azoxymethane in mice

Emi Osawa, Atsushi Nakajima, Koichiro Wada et al. · Gastroenterology · 2003 · 192 citations

Suppress Colon Carcinogenesis, Oncology, Medicine +6

Peroxisome Proliferator-Activated Receptor Gamma Agonist Ligands Stimulate a Th2 Cytokine Response and Prevent Acute Colitis

Lawrence J. Saubermann, Atsushi Nakajima, Koichiro Wada et al. · Inflammatory Bowel Diseases · 2002 · 164 citations · Full text