Takuma Higurashi

Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with nonalcoholic fatty liver disease (NAFLD)

Masato Yoneda, Masato Yoneda, Hironori Mawatari et al. · Digestive and Liver Disease · 2007 · 422 citations

Medicine, Internal Medicine, Pathology +15

Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial

Takuma Higurashi, Kunihiro Hosono, Hirokazu Takahashi et al. · The Lancet Oncology · 2016 · 340 citations

Medicine, Oncology, Pharmacology +9

Serum miR-21, miR-29a, and miR-125b Are Promising Biomarkers for the Early Detection of Colorectal Neoplasia

Atsushi Yamada, Takahiro Horimatsu, Yoshinaga Okugawa et al. · Clinical Cancer Research · 2015 · 157 citations

Medicine, Molecular Medicine, Oncology +17

Gastrointestinal Cancer Stage at Diagnosis Before and During the COVID-19 Pandemic in Japan

Kento Kuzuu, Noboru Misawa, Keiichi Ashikari et al. · JAMA Network Open · 2021 · 144 citations · Full text

Medicine, Clinical Sciences, Oncology +17

Infection of specific strains of Streptococcus mutans, oral bacteria, confers a risk of ulcerative colitis

Ayuchi Kojima, Kazuhiko Nakano, Koichiro Wada et al. · Scientific Reports · 2012 · 130 citations · Full text

Life Sciences, Immunology, Infectious Diseases +12