Rachel Lough

Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity

Srinivas Rao Kasibhatla, Kevin Hong, Marco A. Biamonte et al. · Journal of Medicinal Chemistry · 2007 · 125 citations · Full text

Medicine, Oncology, Pharmacology +14

7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors

Lin Zhang, Junhua Fan, K. NGUYEN VU et al. · Journal of Medicinal Chemistry · 2006 · 114 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis and Biological Evaluation of a New Class of Geldanamycin Derivatives as Potent Inhibitors of Hsp90

Jean‐Yves Le Brazidec, Adeela Kamal, David J. Busch et al. · Journal of Medicinal Chemistry · 2004 · 84 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

EC144 Is a Potent Inhibitor of the Heat Shock Protein 90

Jiandong Shi, Ryan W. Van De Water, Kevin Hong et al. · Journal of Medicinal Chemistry · 2012 · 72 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

BIIB021, a synthetic Hsp90 inhibitor, has broad application against tumors with acquired multidrug resistance

Hong Zhang, Laura Neely, Karen Lundgren et al. · International Journal of Cancer · 2009 · 72 citations

Medicine, Oncology, Pharmacology +14