Srinivas Rao Kasibhatla

BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90

Karen Lundgren, Hong Zhang, John Brekken et al. · Molecular Cancer Therapeutics · 2009 · 168 citations · Full text

MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes

Mark D. Erion, Paul D. van Poelje, Qun Dang et al. · Proceedings of the National Academy of Sciences · 2005 · 162 citations · Full text

Human Fbpase, Aldo-keto Reductase, Chemical Biology +20

Discovery of a Series of Phosphonic Acid-Containing Thiazoles and Orally Bioavailable Diamide Prodrugs That Lower Glucose in Diabetic Animals Through Inhibition of Fructose-1,6-Bisphosphatase

Qun Dang, Yan Liu, Daniel K. Cashion et al. · Journal of Medicinal Chemistry · 2010 · 158 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +14

Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity

Srinivas Rao Kasibhatla, Kevin Hong, Marco A. Biamonte et al. · Journal of Medicinal Chemistry · 2007 · 125 citations · Full text

Chemoprevention Strategy, Molecular Biology, Pharmacotherapy +17

7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors

Lin Zhang, Junhua Fan, K. NGUYEN VU et al. · Journal of Medicinal Chemistry · 2006 · 114 citations · Full text

Pyridino- Thiazolothiopurines, Pharmaceutical Science, Drug Target +18