Paul D. van Poelje

Targeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index

Mark D. Erion, Edward E. Cable, Bruce R. Ito et al. · Proceedings of the National Academy of Sciences · 2007 · 268 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Isolation of a Family of Organic Anion Transporters from Human Liver and Kidney

William Sun, Rong Wu, Paul D. van Poelje et al. · Biochemical and Biophysical Research Communications · 2001 · 219 citations

Engineering, Biochemistry, Nephrology +8

Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist #

Edward E. Cable, Patricia D. Finn, Jeffrey W. Stebbins et al. · Hepatology · 2008 · 209 citations

Medicine, Endocrinology, Pharmacology +16

MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes

Mark D. Erion, Paul D. van Poelje, Qun Dang et al. · Proceedings of the National Academy of Sciences · 2005 · 162 citations

Life Sciences, Biochemistry, Pharmacology +17

Design, Synthesis, and Characterization of a Series of Cytochrome P₄₅₀3A-Activated Prodrugs (HepDirect Prodrugs) Useful for Targeting Phosph(on)ate-Based Drugs to the Liver^§

Mark D. Erion, K. Raja Reddy, Serge H. Boyer et al. · Journal of the American Chemical Society · 2004 · 160 citations

Medicine, Medicinal Chemistry, Pharmacology +17