Paul D. van Poelje

Targeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index

Mark D. Erion, Edward E. Cable, Bruce R. Ito et al. · Proceedings of the National Academy of Sciences · 2007 · 262 citations · Full text

Pharmacotherapy, Fatty Liver Disease, Metabolic Syndrome +18

Isolation of a Family of Organic Anion Transporters from Human Liver and Kidney

William Sun, Rong Wu, Paul D. van Poelje et al. · Biochemical and Biophysical Research Communications · 2001 · 219 citations

Biochemistry, Medicine, Organic Chemistry +4

Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist #

Edward E. Cable, Patricia D. Finn, Jeffrey W. Stebbins et al. · Hepatology · 2008 · 204 citations

MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes

Mark D. Erion, Paul D. van Poelje, Qun Dang et al. · Proceedings of the National Academy of Sciences · 2005 · 162 citations · Full text

Human Fbpase, Aldo-keto Reductase, Chemical Biology +20

Discovery of a Series of Phosphonic Acid-Containing Thiazoles and Orally Bioavailable Diamide Prodrugs That Lower Glucose in Diabetic Animals Through Inhibition of Fructose-1,6-Bisphosphatase

Qun Dang, Yan Liu, Daniel K. Cashion et al. · Journal of Medicinal Chemistry · 2010 · 158 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +14