Yongsong Tian

Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and<i>trans</i>-γ-Hydroxycrotonic Acid (T-HCA) Analogs

Jacob Krall, Claus Jensen, Francesco Bavo et al. · Journal of Medicinal Chemistry · 2017 · 23 citations

The first enantioselective total synthesis of (+)-preussin B and an improved synthesis of (+)-preussin by step-economical methods

Pei‐Qiang Huang, Hui Geng, Yongsong Tian et al. · Science China Chemistry · 2015 · 22 citations

Enantioselective Synthesis, Bioorganic Chemistry, Engineering +11

Discovery of 2-(Imidazo[1,2- <i>b</i> ]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites

Jacob Krall, Francesco Bavo, Christina Birkedahl Falk‐Petersen et al. · Journal of Medicinal Chemistry · 2019 · 19 citations · Full text

Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain

Yongsong Tian, Mohamed A. Shehata, Stine Juul Gauger et al. · Journal of Medicinal Chemistry · 2022 · 14 citations · Full text

Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain

Yongsong Tian, Mohamed A. Shehata, Stine Juul Gauger et al. · Journal of Medicinal Chemistry · 2022 · 12 citations · Full text