Persistent Expression of FLAG-tagged Micro dystrophin in Nonhuman Primates Following Intramuscular and Vascular Delivery

Louise R. Rodino‐Klapac, Chrystal L. Montgomery, William G. Bremer, +10

Molecular Therapy

Homologous Recombination Mediates Functional Recovery of Dysferlin Deficiency following AAV5 Gene Transfer

William E. Grose, K. Reed Clark, Danielle Griffin, +8

PLoS ONE

Viral ReplicationGeneticsMolecular BiologyMolecular GeneticsCellular Physiology +15

Vascular Delivery of rAAVrh74.MCK.GALGT2 to the Gastrocnemius Muscle of the Rhesus Macaque Stimulates the Expression of Dystrophin and Laminin α2 Surrogates

Louis G. Chicoine, Louise R. Rodino‐Klapac, Guohong Shao, +15

Molecular Therapy

Micro-dystrophin and follistatin co-delivery restores muscle function in aged DMD model

Louise R. Rodino‐Klapac, Paul M.L. Janssen, Kimberly M. Shontz, +10

Human Molecular Genetics

Muscle FunctionEngineeringAgingBiomedical EngineeringOrthopaedic Surgery +19

AAV1.NT-3 gene therapy increases muscle fiber diameter through activation of mTOR pathway and metabolic remodeling in a CMT mouse model

Mehmet E. Yalvaç, Jakkrit Amornvit, Lei Chen, +3

Gene Therapy

Molecular PhysiologySignaling PathwayBiomedical ResearchSkeletal MuscleCell Signaling +10

Deconstructing tissue engineered trachea: Assessing the role of synthetic scaffolds, segmental replacement and cell seeding on graft performance

Sayali Dharmadhikari, Lumei Liu, Kimberly M. Shontz, +8

Acta Biomaterialia

Regenerative MedicineTissue EngineeringEngineeringGraft PerformanceBioengineering Model +10

The Effect of Phenotype on Mechanical Stretch-Induced Vascular Smooth Muscle Cell Apoptosis

Baogen Y. Su, Kimberly M. Shontz, Nicholas A. Flavahan, +1

Journal of Vascular Research

Muscle FunctionEngineeringApoptosisCell DeathDifferentiated Vsmc +14

Regeneration of partially decellularized tracheal scaffolds in a mouse model of orthotopic tracheal replacement

Lumei Liu, Sayali Dharmadhikari, Kimberly M. Shontz, +9

Journal of Tissue Engineering

Impaired regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis

Mehmet E. Yalvaç, Jakkrit Amornvit, Cilwyn Braganza, +7

Skeletal Muscle

Tissue-engineered composite tracheal grafts create mechanically stable and biocompatible airway replacements

Lumei Liu, Sayali Dharmadhikari, Barak M. Spector, +12

Journal of Tissue Engineering

Tissue EngineeringLung TransplantationEngineeringBiofabricationTissue Transplantation +17