Bruno Sáinz

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells

Patricia Sancho, Emma Burgos‐Ramos, Alejandra Tavera-Tapia et al. · Cell Metabolism · 2015 · 708 citations · Full text

Tumor Biology, Lineage Plasticity, Pancreatic Cancer +12

Identification of the Niemann-Pick C1–like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor

Bruno Sáinz, Naina Barretto, Danyelle N. Martin et al. · Nature Medicine · 2012 · 435 citations

Molecular Virology, Hepatology, Viral Hepatitis +7

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

Dietrich Alexander Ruess, Guus J.J.E. Heynen, Katrin J. Ciecielski et al. · Nature Medicine · 2018 · 363 citations

Tumor Biology, Mutant Kras-driven Cancers, Cancer Cell Biology +4

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

Paola Martinelli, Enrique Carrillo de Santa Pau, Trevor F. Cox et al. · Gut · 2016 · 266 citations · Full text

Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms

Michele Cioffi, Sara Maria David Trabulo, Manuel Hidalgo et al. · Clinical Cancer Research · 2015 · 235 citations