Virginia C. Hughes

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Nicholas W. Gale, Melissa G. Dominguez, Irene Noguera et al. · Proceedings of the National Academy of Sciences · 2004 · 595 citations · Full text

Developmental Biology, Angiogenesis, Embryonic Lethality +12

Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control

Klas Kullander, Susan D. Croll, Manuel Zimmer et al. · Genes & Development · 2001 · 257 citations · Full text

Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor

Pan Li, Xiaoman Yang, Virginia C. Hughes et al. · Proceedings of the National Academy of Sciences · 2011 · 151 citations · Full text

Organ Development, Cellular Physiology, Angiogenesis +26

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis

Melissa G. Dominguez, Virginia C. Hughes, Pan Li et al. · Proceedings of the National Academy of Sciences · 2007 · 142 citations · Full text

Endothelial Cell Pathobiology, Vascular Disease, Angiogenesis +14

Monoallelic BMP2 Variants Predicted to Result in Haploinsufficiency Cause Craniofacial, Skeletal, and Cardiac Features Overlapping Those of 20p12 Deletions

Tiong Yang Tan, Claudia Gonzaga‐Jauregui, Elizabeth Bhoj et al. · The American Journal of Human Genetics · 2017 · 58 citations · Full text

Monoallelic Bmp2 Variants, Craniofacial Disorder, Genetic Disorder +9