E. Themis Joannides

3-Aminoquinazolinediones as a New Class of Antibacterial Agents Demonstrating Excellent Antibacterial Activity Against Wild-Type and Multidrug Resistant Organisms

Edmund L. Ellsworth, Tuan P. Tran, Hollis D. Showalter et al. · Journal of Medicinal Chemistry · 2006 · 62 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Antibiotic Adjuvant +19

Structure-activity relationships of quinolone agents against mycobacteria: effect of structural modifications at the 8 position

Thomas E. Renau, Jeffrey W. Gage, J A Dever et al. · Antimicrobial Agents and Chemotherapy · 1996 · 52 citations · Full text

Structure–activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors

Tuan P. Tran, Edmund L. Ellsworth, Joseph P. Sanchez et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 51 citations

Molecular Pharmacology, Antimicrobial Drug Discovery, Biochemistry +12

New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8-fluoro group with reduced phototoxic risk

Joseph P. Sanchez, Alexander J. Bridges, R. A. BUCSH et al. · Journal of Medicinal Chemistry · 1992 · 25 citations

Mouse Phototolerance Assay, Drug Resistance, Medicinal Chemistry +17

Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones

Kim Hutchings, Tuan P. Tran, Edmund L. Ellsworth et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 23 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +11