Concepedia

Structure–activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors

Tuan P. Tran, Edmund L. Ellsworth, Joseph P. Sanchez, Brian M. Watson, Michael A. Stier, Hollis D. Showalter, John M. Domagala, Martin A. Shapiro, E. Themis Joannides, Stephen J. Gracheck,

Bioorganic & Medicinal Chemistry Letters · 2006 · 51 citations · 15 references

DOI

Concepts

References

15

Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically

Mary Jane Ferraro · 2000 · 16.9K citations

, , +10

1,8-Naphthyridine Derivatives. A New Class of Chemotherapeutic Agents

George Y. Lesher, Ernest J. Froelich, M. D. GRUETT et al. · Journal of Medicinal Chemistry · 1962 · 755 citations

, , +6

Structure-activity relationships of antibacterial 6,7- and 7,8-disubstituted 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids

Hiroshi Koga, Akira Itoh, Satoshi Murayama et al. · Journal of Medicinal Chemistry · 1980 · 483 citations

, , +13

Synthesis and Antibacterial Activity of a Novel Series of Potent DNA Gyrase Inhibitors. Pyrazole Derivatives

Akihiko Tanitame, Yoshihiro Oyamada, Keiko Ofuji et al. · Journal of Medicinal Chemistry · 2004 · 288 citations · Full text

, , +16

New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay

John M. Domagala, Lori Doyle Hanna, Carl L. Heifetz et al. · Journal of Medicinal Chemistry · 1986 · 265 citations

, , +9