Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

Christophe Le Tourneau, Jean-Pierre Delord, Anthony Gonçalvès, +20

The Lancet Oncology

Advanced CancerDrug TargetingOncologyMedicineVersus Conventional Therapy +10

<i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma

Simon J. Furney, Malin Pedersen, David Gentien, +9

Cancer Discovery

Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)

Fabrice André, Thomas Bachelot, Frédéric Commo, +17

The Lancet Oncology

Dna SequencingMetastatic Breast CancerBreast OncologyTumor HeterogeneityMedicine +9

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

Barbara Piasecka, Darragh Duffy, Alejandra Urrutia, +52

Proceedings of the National Academy of Sciences

A gene-expression profiling score for prediction of outcome in patients with follicular lymphoma: a retrospective training and validation analysis in three international cohorts

Sarah Huet, Bruno Tesson, Jean‐Philippe Jais, +27

The Lancet Oncology

Lymphoid NeoplasiaOncologyMedicineRetrospective TrainingPredictive Analytics +10

Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer

Virginie Maire, Fariba Némati, Marion Richardson, +18

Cancer Research

Breast OncologyTnbc Cell LinesPathologyCell DeathCancer Biology +18

Molecular profiling of patient-derived breast cancer xenografts

Fabien Reyal, Charlotte Guyader, Charles Decraene, +15

Breast Cancer Research

Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors

Fariba Némati, Xavier Sastre‐Garau, Cécile Laurent, +18

Clinical Cancer Research

Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target

Nabil Amirouchene-Angelozzi, Fariba Némati, David Gentien, +11

Molecular Oncology

TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast Cancer

Virginie Maire, Céline Baldeyron, Marion Richardson, +15

PLoS ONE

Breast OncologyMedicinePathologyCell DeathCancer Genomics +10