Helena Thörn

<i>In Silico</i> Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models

Erik Sjögren, Helena Thörn, Christer Tannergren · Molecular Pharmaceutics · 2016 · 95 citations

Gastrointestinal Pharmacology, Gastroenterology, Incomplete Gi Absorption +17

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Alison Margolskee, Adam S. Darwich, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 66 citations · Full text

Pharmacokinetic Modeling, Medicine, Process Analytical Technology +6

Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans

Helena Thörn, Anna Lundahl, J. A. Schrickx et al. · European Journal of Pharmaceutical Sciences · 2011 · 62 citations

Cyp2d6 Substrates, Biochemistry, Medicine +5

Pulmonary absorption – estimation of effective pulmonary permeability and tissue retention of ten drugs using an ex vivo rat model and computational analysis

Johanna Eriksson, Erik Sjögren, Helena Thörn et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 47 citations

Pulmonary Circulation, Lung Deposition, Medicine +13

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Adam S. Darwich, Alison Margolskee, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 45 citations · Full text

Systems Pharmacology, Silico Performance, Pharmacokinetic Modeling +13