West Nile Virus 5′-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2′-O Methylations by Nonstructural Protein 5

Debashish Ray, Aaloki Shah, Mark Tilgner, +7

Journal of Virology

Viral ReplicationViral Polymerase StructureGeneticsMolecular BiologyViral Structural Protein +16

Infectious cDNA Clone of the Epidemic West Nile Virus from New York City

Pei‐Yong Shi, Mark Tilgner, Michael K. Lo, +2

Journal of Virology

Functional Analysis of Mosquito-Borne Flavivirus Conserved Sequence Elements within 3′ Untranslated Region of West Nile Virus by Use of a Reporting Replicon That Differentiates between Viral Translation and RNA Replication

Michael K. Lo, Mark Tilgner, Kristen A. Bernard, +1

Journal of Virology

Viral ReplicationRna ReplicationEngineeringViral Polymerase StructureViral Polymerase Mechanism +18

Inhibition of Flavivirus Infections by Antisense Oligomers Specifically Suppressing Viral Translation and RNA Replication

Tia S. Deas, Iwona Binduga-Gajewska, Mark Tilgner, +7

Journal of Virology

Viral ReplicationRna ReplicationMolecular VirologySynthetic VirologyPathogenesis +12

Construction and Characterization of Subgenomic Replicons of New York Strain of West Nile Virus

Pei‐Yong Shi, Mark Tilgner, Michael K. Lo

Virology

Viral EvolutionNew York StrainGeneticsPathogenesisVirology +9

Triaryl Pyrazoline Compound Inhibits Flavivirus RNA Replication

Francesc Puig‐Basagoiti, Mark Tilgner, Brett M. Forshey, +9

Antimicrobial Agents and Chemotherapy

High-Throughput Assays Using a Luciferase-Expressing Replicon, Virus-Like Particles, and Full-Length Virus for West Nile Virus Drug Discovery

Francesc Puig‐Basagoiti, Tia S. Deas, Ping Ren, +3

Antimicrobial Agents and Chemotherapy

Viral DiagnosticsViral Polymerase MechanismMany FlavivirusesAntiviral DrugFull-length Virus +16

In Vitro Resistance Selection and In Vivo Efficacy of Morpholino Oligomers against West Nile Virus

Tia S. Deas, Corey J. Bennett, Susan Jones, +8

Antimicrobial Agents and Chemotherapy

Synthetic VirologyImmunologyViral PathogenesisAntiviral DrugDrug Resistance +16

The flavivirus-conserved penta-nucleotide in the 3′ stem-loop of the West Nile virus genome requires a specific sequence and structure for RNA synthesis, but not for viral translation

Mark Tilgner, Tia S. Deas, Pei‐Yong Shi

Virology

Virus StructureViral ReplicationViral Polymerase StructureGeneticsViral Polymerase Mechanism +11

Structure and Function of the 3′ Terminal Six Nucleotides of the West Nile Virus Genome in Viral Replication

Mark Tilgner, Pei‐Yong Shi

Journal of Virology

Viral ReplicationViral Polymerase StructureGeneticsViral Polymerase MechanismWn Virus Genome +17