Christine Chang

Molecular Cloning and Expression of an Avian Macrophage Nitric-oxide Synthase cDNA and the Analysis of the Genomic 5′-Flanking Region

Arthur Lin, Christine Chang, Charles C. McCormick · Journal of Biological Chemistry · 1996 · 133 citations · Full text

A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors

Sue J. Sohn, Kathy Barrett, Anne van Abbema et al. · The Journal of Immunology · 2013 · 123 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +25

Lead Optimization of a 4-Aminopyridine Benzamide Scaffold To Identify Potent, Selective, and Orally Bioavailable TYK2 Inhibitors

Jun Liang, Anne van Abbema, Mercedesz Balázs et al. · Journal of Medicinal Chemistry · 2013 · 97 citations · Full text

Pharmaceutical Research, Immunology, Lead Identification +24

Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors

Janusz J. Kulagowski, Wade Blair, Richard J. Bull et al. · Journal of Medicinal Chemistry · 2012 · 91 citations · Full text

Rheumatology, Medicinal Chemistry, Drug Target +15

Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Emily J. Hanan, Anne van Abbema, Kathy Barrett et al. · Journal of Medicinal Chemistry · 2012 · 89 citations · Full text

Lead Compounds, Drug Target, Chemoprevention Strategy +19