Kevin Drenner

Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration

Ze’ev Melamed, Jone López‐Erauskin, Michael W. Baughn et al. · Nature Neuroscience · 2019 · 667 citations

Life Sciences, Genetics, Molecular Biology +13

Targeted degradation of sense and antisense <i>C9orf72</i> RNA foci as therapy for ALS and frontotemporal degeneration

Clotilde Lagier‐Tourenne, Michael W. Baughn, Frank Rigo et al. · Proceedings of the National Academy of Sciences · 2013 · 557 citations · Full text

Life Sciences, Neurobiology, Neurology +14

Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

Jie Jiang, Qiang Zhu, Tania F. Gendron et al. · Neuron · 2016 · 540 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

Jelena Scekic‐Zahirovic, Oliver Sendscheid, Hajer El Oussini et al. · The EMBO Journal · 2016 · 242 citations · Full text

Life Sciences, Genetics, Neuroscience +17

C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation

Weiwei Cheng, Shaopeng Wang, Alexander A. Mestre et al. · Nature Communications · 2017 · 219 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17